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产品信息
PA5-52265
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human MRPL40. Recombinant protein control fragment (Product #RP-91336).
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644149
产品详细信息
Immunogen sequence: TQLRETQELI PIEDFITPLK FLDKARERPQ VELTFEETER RALLLKKWSL YKQQERKMER DTIRAMLEAQ QEALEELQLE SPKLHAEAIK RDPNLFPFEK EGPHYTPPIP NYQPPEGRYN DITK
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 77%.
靶标信息
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 39S ribosomal protein L40, mitochondrial; L40mt; Large ribosomal subunit protein mL40; MRP-L40; nuclear localization signal protein absent in velo-cardio-facial patients; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog; Up-regulated in metastasis
基因别名: L40mt; MRP-L22; MRP-L40; MRPL22; MRPL40; NLVCF; URIM
UniProt ID: (Human) Q9NQ50, (Rat) P83565, (Mouse) Q9Z2Q5
Entrez Gene ID: (Human) 64976, (Rat) 287962, (Mouse) 18100
