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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p.
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蛋白别名: 39S ribosomal protein L48, mitochondrial; L48mt; Large ribosomal subunit protein mL48; MGC13323
基因别名: CGI-118; HSPC290; L48MT; MRP-L48; MRPL48
UniProt ID: (Human) Q96GC5
Entrez Gene ID: (Human) 51642