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产品信息
PA5-52249
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644189
产品详细信息
Immunogen sequence: TKKPTFMDEE VQSILTKMTG LNLQKTFKPA IQELKPPTYK LMTQAQLEEA TRQAVEAAKV RLKMPPVLEE RVPINDVLAE DKILEGTETT KYVFTDISYS IPHRERFIVV REPSGTLRKA
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 93%.
靶标信息
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 28S ribosomal protein S22, mitochondrial; MRP-S22; ribosomal protein, mitochondrial, S22; S22mt; Small ribosomal subunit protein mS22
基因别名: 3100002P07Rik; C3orf5; COXPD5; GIBT; GK002; MRP-S22; MRPS22; RPMS22
UniProt ID: (Human) P82650, (Mouse) Q9CXW2
Entrez Gene ID: (Human) 56945, (Mouse) 64655, (Rat) 683519
