Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 3
MST3 Antibody (PA5-22269) in IHC (P)
STK24 antibody [N2C1], Internal detects STK24 protein at cytosol and nucleus on human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. STK24 antibody [N2C1], Internal (Product # PA5-22269) dilution: 1:250. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-22269
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 137 and 231 of MST3 (Uniprot ID#Q9Y6E0)
偶联物
形式
Liquid
浓度
0.94 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152408
产品详细信息
Recommended positive controls: 293T, A431, H1299, HeLa, Raji, rat brain.
Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
STK24 (MST3) is a serine/threonine kinase that is a member of the GCK subfamily of STE20-like proteins. The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: epididymis secretory protein Li 95; Mammalian STE20-like protein kinase 3; MST-3; OTTHUMP00000018594; RP11-111L24.5; serine/threonine kinase 24 (STE20 homolog, yeast); Serine/threonine-protein kinase 24; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3
基因别名: HEL-S-95; MST-3; MST3; MST3B; RGD1561742; STE20; STK24; STK3
UniProt ID: (Human) Q9Y6E0, (Rat) B0LT89
Entrez Gene ID: (Human) 8428, (Rat) 361092
mitotic cell cycle
protein phosphorylation
cellular component disassembly involved in execution phase of apoptosis
signal transduction
intrinsic apoptotic signaling pathway in response to oxidative stress
signal transduction by protein phosphorylation
negative regulation of cell migration
response to hydrogen peroxide
protein autophosphorylation
regulation of axon regeneration
execution phase of apoptosis
cell-cell adhesion
apoptotic process
intracellular signal transduction
positive regulation of axon regeneration
