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MTMR2 Antibody (A304-535A-T) in WB
Detection of human and mouse MTMR2 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-MTMR2 antibody (Product # A304-535A) (lot A304-535A-1) used for WB at 0.4 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
产品信息
A304-535A-T
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1 to 50 of human Myotubularin Related Protein 2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Bovine and Orangutan
靶标信息
This gene is a member of the myotubularin family. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Multiple alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Myotubularin-related protein 2; phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2; phosphatidylinositol-3-phosphatase; Phosphatidylinositol-3-phosphate phosphatase; phosphoinositide-3-phosphatase
基因别名: 6030445P13Rik; CMT4B; CMT4B1; KIAA1073; MTMR2
UniProt ID: (Human) Q13614, (Mouse) Q9Z2D1
Entrez Gene ID: (Human) 8898, (Mouse) 77116
phosphatidylinositol-3-phosphatase activity
protein tyrosine phosphatase activity
protein binding
protein tyrosine/serine/threonine phosphatase activity
protein homodimerization activity
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
hydrolase activity
phosphatase activity
phosphatidylinositol phosphate phosphatase activity
phosphatase
negative regulation of receptor internalization
protein dephosphorylation
phosphatidylinositol biosynthetic process
negative regulation of myelination
myelin assembly
peptidyl-tyrosine dephosphorylation
negative regulation of endocytosis
inositol phosphate dephosphorylation
phosphatidylinositol dephosphorylation
neuron development
protein tetramerization
negative regulation of excitatory postsynaptic potential
dendritic spine maintenance
positive regulation of early endosome to late endosome transport
negative regulation of receptor catabolic process
lipid metabolic process
dephosphorylation
phosphatidylinositol metabolic process
