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产品信息
MA5-24557
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1E11
抗原
MTMR3 (NP_066576.1, 579 a.a. ~ 674 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
纯化类型
Protein A
保存液
PBS, pH 7.2
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2633529
产品详细信息
Peptide Sequence: CPSPTTPVDD SCAPYPAPGT SPDDPPLSRL PKTRSYDNLT TACDNTVPLA SRRCSDPSLN EKWQEHRRSL ELSSLAGPGE DPLSADSLGK PTRVPG
靶标信息
This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-bisphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FYVE (Fab1 YGLO23 Vsp27 EEA1 domain) dual-specificity protein phosphatase; FYVE domain-containing dual specificity protein phosphatase 1; FYVE-DSP1; Myotubularin-related protein 3; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3; Phosphatidylinositol-3-phosphate phosphatase; Zinc finger FYVE domain-containing protein 10; zinc finger, FYVE domain containing 10
基因别名: FYVE-DSP1; KIAA0371; MTMR3; ZFYVE10
UniProt ID: (Human) Q13615
Entrez Gene ID: (Human) 8897
