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This gene encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase, Rab-like GTPase activator and myotubularins domain, the Rac-induced recruitment domain, the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9, enhancer-of-zeste, and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 1, 3-bisphosphate. A pseudogene of this gene is found on chromosome 5.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp781E194; Inositol 1,3-bisphosphate phosphatase; MGC163449; MGC163451; Myotubularin-related protein 7; Phosphatidylinositol-3-phosphate phosphatase MTMR7
基因别名: MTMR7
UniProt ID: (Human) Q9Y216, (Mouse) Q9Z2C9
Entrez Gene ID: (Human) 9108, (Mouse) 54384