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MTPN Antibody (A305-473A) in WB
Detection of human and mouse MTPN by western blot. Samples: Whole cell lysate (15 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-MTPN antibody (Product # A305-473A) (lot A305-473A-1) used for WB at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A305-473A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 68 to 118 of human Myotrophin.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rat, Bovine and Dog
Target Information
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6. 4 kDa tumor antigen that is associated with myeloproliferative disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Granule cell differentiation protein; Myotrophin; Protein V-1
Gene Aliases: 5033418D15Rik; GCDP; MTPN; V-1; V1
UniProt ID: (Human) P58546, (Mouse) P62774
Entrez Gene ID: (Human) 136319, (Mouse) 14489
regulation of translation
catecholamine metabolic process
positive regulation of macromolecule biosynthetic process
positive regulation of cardiac muscle hypertrophy
cell growth
regulation of striated muscle tissue development
cerebellar granule cell differentiation
neuron differentiation
positive regulation of cell growth
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
striated muscle cell differentiation
positive regulation of protein metabolic process
cellular response to mechanical stimulus
regulation of barbed-end actin filament capping
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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