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MUT Antibody (MA5-49182) in IHC (P)
Immunohistochemistry analysis of MUT in paraffin-embedded section of human mammary cancer tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. Samples were incubated with MUT Monoclonal antibody (Product # MA5-49182) using a dilution of 1 μg/mL overnight at 4°C. Biotinylated goat anti-mouse IgG was used... View More
Product Details
MA5-49182
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
2D6
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human MUT (33-65aa LHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPE).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_3074840
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Immunogen sequence is different from the related mouse sequence by one amino acid.
Positive Control - WB: human Hela whole cell, human K562 whole cell, human HEK293 whole cell, human PC-3 whole cell, human Caco-2 whole cell, human Raji whole cell, rat PC-12 whole cell, mouse NIH/3T3 whole cell. IHC: human mammary cancer tissue, human rectal cancer tissue, human rectal cancer tissue, rat intestine tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MCM; methylmalonyl CoA mutase; methylmalonyl Coenzyme A mutase; Methylmalonyl-CoA isomerase; Methylmalonyl-CoA mutase, mitochondrial; methylmalonyl-Coenzyme A mutase; mutant methylmalonyl CoA mutase; truncated methylmalonyl CoA mutase
Gene Aliases: D230010K02Rik; MCM; MMUT; MUT
UniProt ID: (Human) P22033, (Mouse) P16332
Entrez Gene ID: (Human) 4594, (Mouse) 17850, (Rat) 688517
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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