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MUTED Antibody (PA5-23648) in IHC (P)
Immunohistochemistry analysis of MUTED in formalin fixed and paraffin embedded human tonsil tissue. Samples were incubated with MUTED polyclonal antibody (Product # PA5-23648) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
产品信息
PA5-23648
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 40-68 amino acids from the central region of human MUTED
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2541148
产品详细信息
This antibody is predicted to react with porcine based on sequence homology.
靶标信息
This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: biogenesis of lysosomal organelles complex-1, subunit 5, muted; Biogenesis of lysosome-related organelles complex 1 subunit 5; biogenesis of organelles complex-1, subunit 5, muted; BLOC-1 subunit 5; muted homolog; Protein Muted homolog
基因别名: 1810074A19Rik; BLOC1S5; BLOS5; MU; MUTED
UniProt ID: (Human) Q8TDH9, (Mouse) Q8R015
Entrez Gene ID: (Human) 63915, (Mouse) 17828
anterograde axonal transport
neuron projection development
melanosome transport
melanosome organization
endosome to melanosome transport
anterograde synaptic vesicle transport
positive regulation of pigment cell differentiation
vesicle-mediated transport
otolith morphogenesis
developmental pigmentation
