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产品信息
PA5-59772
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644317
产品详细信息
Immunogen sequence: LGATDTAVFD VRLSGKTKTV PGYLRIGDMG GFAIWCKKAK APRPVPKPRG LSRDMQGLSL DAASQPSKGG LLERTASRLG SRASTL
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 73%.
靶标信息
FAM125A, also named as MVB12A and CFBP, is a component of the ESCRT-I complex. FAM125A is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. FAM125A has three isoforms with MW 27-28 kDa and 25 kDa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CIN85/CD2AP family binding protein; CIN85/CD2AP family-binding protein; ESCRT-I complex subunit MVB12A; family with sequence similarity 125, member A; Multivesicular body subunit 12A; Protein FAM125A
基因别名: CFBP; FAM125A; MVB12A
UniProt ID: (Human) Q96EY5
Entrez Gene ID: (Human) 93343
autophagy
protein transport
virus maturation
multivesicular body assembly
viral budding via host ESCRT complex
regulation of epidermal growth factor receptor signaling pathway
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
positive regulation of viral process
regulation of viral budding via host ESCRT complex
