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产品信息
PA5-22164
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 156 and 371 of MVD (Uniprot ID#P53602)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152719
产品详细信息
Recommended positive controls: 293T, A431, HeLa, A375, mouse Liver.
Predicted reactivity: Mouse (81%), Rat (81%), Rhesus Monkey (94%), Bovine (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Diphosphomevalonate decarboxylase; MDDase; mevalonate (diphospho) decarboxylase; Mevalonate (diphospho)decarboxylase; Mevalonate pyrophosphate decarboxylase
基因别名: C78718; FP17780; MDDase; MPD; MVD; POROK7
UniProt ID: (Human) P53602, (Mouse) Q99JF5
Entrez Gene ID: (Human) 4597, (Mouse) 192156
dolichyl diphosphate biosynthetic process
cholesterol biosynthetic process
positive regulation of cell proliferation
isoprenoid biosynthetic process
isopentenyl diphosphate biosynthetic process, mevalonate pathway
lipid metabolic process
steroid biosynthetic process
steroid metabolic process
cholesterol metabolic process
sterol biosynthetic process
