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产品信息
H00004603-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
2A2
抗原
MYBL1 (XP_034274, 625 a.a. approximately 734 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: KSLVLDNWEK EESGTQLLTE DISDMQSENR FTTSLLMIPL LEIHDNRCNL IPEKQDINST NKTYTLTKKK PNPNTSKVVK LEKNLQSNCE WETVVYGKTE DQLIMTEQAR
靶标信息
A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t(14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A-Myb; Myb-like protein 1; Myb-related protein A; MYBA; v-myb avian myeloblastosis viral oncogene homolog-like 1; VMYB
基因别名: A-MYB; AMYB; MYBL1
UniProt ID: (Human) P10243
Entrez Gene ID: (Human) 4603
