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MYF5 Antibody (PA5-47565) in ICC/IF
Immunocytochemistry analysis of MYF5 in immersion fixed C2C12 mouse myoblast cell line undifferentiated (upper panel) or differentiated with horse serum for 7 days (lower panel). Samples were incubated in MYF5 polyclonal antibody (Product # PA5-47565) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red) and counterstained with DAPI (blue).
产品信息
PA5-47565
产品规格
种属反应
Human,
Mouse
已发表种属
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived recombinant human MYF-5 Met1-Leu255
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609454
产品详细信息
This antibody detects recombinant human MYF-5 in direct ELISAs and Western blots.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
MYF5 is a member of the myogenic basic helix-loop-helix family of transcription factors, which can activate the muscle differentiation program.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: bHLHc2; Class C basic helix-loop-helix protein 2; Myf-5; Myogenic factor 5; myogenic regulatory factor MYF-5
基因别名: B130010J22Rik; BHLHC2; Myf-5; MYF5
UniProt ID: (Human) P13349, (Mouse) P24699
Entrez Gene ID: (Human) 4617, (Mouse) 17877
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein binding
protein heterodimerization activity
E-box binding
DNA binding
sequence-specific DNA binding
protein dimerization activity
basic helix-loop-helix transcription factor
cartilage condensation
ossification
somitogenesis
regulation of cell-matrix adhesion
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
muscle organ development
skeletal muscle tissue development
extracellular matrix organization
skeletal muscle cell differentiation
muscle cell fate commitment
camera-type eye development
positive regulation of myoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal system morphogenesis
positive regulation of skeletal muscle fiber development
positive regulation of muscle cell differentiation
muscle tissue morphogenesis
positive regulation of myoblast fusion
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
cell differentiation
muscle organ morphogenesis
