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Product Details
PA5-116555
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MYH6/alpha-MHC (NP_0024622)
Conjugate
Form
Liquid
Concentration
0.71 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901186
Product Specific Information
Positive Samples: Mouse skeletal muscle
Immunogen sequence: MTDAQMADFG AAAQYLRKSE KERLEAQTRP FDIRTECFVP DDKEEFVKAK ILSREGGKVI AETENGKTVT VKEDQVLQQN PPKFDKIEDM AMLTFLHEPA VLFNLKERYA AWMIYTYSGL FCVTVNPYKW LPVYNAEVVA AYRGKKRSEA PPHIFSISDN AYQYMLTDRE NQSILITGES GAGKTVNTKR VIQYFASIAA IGDRGKKDNA NANKGTLEDQ IIQANPALEA FGNAKTVRND NSSRFGKFIR
Target Information
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha cardiac MHC; alpha myosin; cardiac myosin heavy chain alpha isoform; cardiomyopathy, hypertrophic 1; MyHC-alpha; myosin 6; Myosin heavy chain 6; myosin heavy chain polypeptide 6 cardiac muscle adult; Myosin heavy chain, cardiac muscle alpha isoform; Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha); myosin heavy chain, cardiac muscle, adult; myosin heavy chain, polypeptide 6, cardiac muscle, alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha; Myosin-6
Gene Aliases: A830009F23Rik; AA517445; alpha-MHC; Myh6; Myhc-a; Myhca
UniProt ID: (Mouse) Q02566
Entrez Gene ID: (Mouse) 17888, (Rat) 29556
microfilament motor activity
nucleotide binding
motor activity
actin binding
protein binding
calmodulin binding
ATP binding
ATPase activity
protein kinase binding
actin-dependent ATPase activity
calcium-dependent ATPase activity
identical protein binding
protein homodimerization activity
protein heterodimerization activity
in utero embryonic development
regulation of the force of heart contraction
regulation of heart rate
muscle contraction
striated muscle contraction
adult heart development
visceral muscle development
regulation of heart contraction
metabolic process
regulation of blood pressure
actin filament-based movement
muscle filament sliding
myofibril assembly
BMP signaling pathway
regulation of ATPase activity
sarcomere organization
ATP metabolic process
cardiac muscle fiber development
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
canonical Wnt signaling pathway
regulation of heart growth
response to heat
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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