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产品信息
PA5-116555
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human MYH6/alpha-MHC (NP_0024622)
偶联物
形式
Liquid
浓度
0.71 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901186
产品详细信息
Positive Samples: Mouse skeletal muscle
Immunogen sequence: MTDAQMADFG AAAQYLRKSE KERLEAQTRP FDIRTECFVP DDKEEFVKAK ILSREGGKVI AETENGKTVT VKEDQVLQQN PPKFDKIEDM AMLTFLHEPA VLFNLKERYA AWMIYTYSGL FCVTVNPYKW LPVYNAEVVA AYRGKKRSEA PPHIFSISDN AYQYMLTDRE NQSILITGES GAGKTVNTKR VIQYFASIAA IGDRGKKDNA NANKGTLEDQ IIQANPALEA FGNAKTVRND NSSRFGKFIR
靶标信息
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
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生物信息学
蛋白别名: alpha cardiac MHC; alpha myosin; cardiac myosin heavy chain alpha isoform; cardiomyopathy, hypertrophic 1; MyHC-alpha; myosin 6; Myosin heavy chain 6; myosin heavy chain polypeptide 6 cardiac muscle adult; Myosin heavy chain, cardiac muscle alpha isoform; Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha); myosin heavy chain, cardiac muscle, adult; myosin heavy chain, polypeptide 6, cardiac muscle, alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha; Myosin-6
基因别名: A830009F23Rik; AA517445; alpha-MHC; Myh6; Myhc-a; Myhca
UniProt ID: (Mouse) Q02566
Entrez Gene ID: (Mouse) 17888, (Rat) 29556
microfilament motor activity
nucleotide binding
motor activity
actin binding
protein binding
calmodulin binding
ATP binding
ATPase activity
protein kinase binding
actin-dependent ATPase activity
calcium-dependent ATPase activity
identical protein binding
protein homodimerization activity
protein heterodimerization activity
in utero embryonic development
regulation of the force of heart contraction
regulation of heart rate
muscle contraction
striated muscle contraction
adult heart development
visceral muscle development
regulation of heart contraction
metabolic process
regulation of blood pressure
actin filament-based movement
muscle filament sliding
myofibril assembly
BMP signaling pathway
regulation of ATPase activity
sarcomere organization
ATP metabolic process
cardiac muscle fiber development
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
canonical Wnt signaling pathway
regulation of heart growth
response to heat
