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Invitrogen
MYH6 Monoclonal Antibody (CL2148)
Product Details
MA5-24631
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
CL2148
Immunogen
Recombinant protein corresponding to Human MYH6
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2637246
Product Specific Information
Immunogen sequence: QVEEDKVNSL SKSKVKLEQQ VDDLEGSLEQ EKKVRMDLER AKRKLEGDLK LTQESIMDLE NDKLQLEEKL KKKEFDINQQ NSKIEDEQVL ALQLQKKLKE NQARIEELEE ELEAERTARA KVEKLRSDLS RELEEISERL EEA
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%.
Binds to an epitope located within the peptide sequence LTQESIMDLENDKLQ as determined by overlapping synthetic peptides.
Target Information
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MyHC-alpha; myosin 6; Myosin heavy chain 6; Myosin heavy chain, cardiac muscle alpha isoform; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); Myosin-6
Gene Aliases: alpha-MHC; ASD3; CMD1EE; CMH14; MYH6; MYHC; MYHCA; SSS3
UniProt ID: (Human) P13533
Entrez Gene ID: (Human) 4624
in utero embryonic development
regulation of the force of heart contraction
regulation of heart rate
protein dephosphorylation
muscle contraction
striated muscle contraction
adult heart development
visceral muscle development
regulation of heart contraction
regulation of blood pressure
muscle filament sliding
myofibril assembly
BMP signaling pathway
regulation of ATPase activity
sarcomere organization
ATP metabolic process
cardiac muscle fiber development
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
canonical Wnt signaling pathway
regulation of heart growth
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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