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产品信息
PA5-54328
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644360
产品详细信息
Immunogen sequence: RFSFSQRSRD ESASETSTPS EHSAAPSPQV EVRTLEGQLV QHPGPGIPRP GHRSRAPELV TKKFPVDLRL PPVVPLPPPT LRELELQRRP TGDFGFSLRR TTMLDRGPEG QACRRVVHFA EP
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.
靶标信息
MYO18A may link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MAJN; Molecule associated with JAK3 N-terminus; myosin 18A; Myosin containing a PDZ domain; myosin containing PDZ domain; myosin-XVIIIa; SP-A receptor subunit SP-R210 alphaS; SP-R210; Surfactant protein receptor SP-R210; Unconventional myosin-XVIIIa
基因别名: CD245; KIAA0216; MYO18A; MYSPDZ; SPR210; TIAF1
UniProt ID: (Human) Q92614
Entrez Gene ID: (Human) 399687
