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产品信息
PA5-44537
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human MYO1C (aa 178-227).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2610549
产品详细信息
Peptide sequence: NPVLEAFGNA KTLRNDNSSR FGKYMDVQFD FKGAPVGGHI LSYLLEKSRV
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
靶标信息
MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.
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生物信息学
蛋白别名: FLJ23903; MMI-beta; Myosin I beta; myosin-I beta; myosin-Ic; nuclear myosin I; Unconventional myosin-Ic
基因别名: MMI-beta; MMIb; MYO1C; myr2; NMI
UniProt ID: (Human) O00159
Entrez Gene ID: (Human) 4641
protein targeting
protein targeting to membrane
positive regulation of cell migration
positive regulation of cell migration by vascular endothelial growth factor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of gene expression, epigenetic
mRNA transport
positive regulation of protein targeting to membrane
positive regulation of vascular endothelial growth factor signaling pathway
regulation of bicellular tight junction assembly
