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Product Details
PA5-81969
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MYO1C. Recombinant protein control fragment (Product #RP-100988).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2789130
Product Specific Information
Immunogen sequence: GEEETLRRLG LERNPQSYLY LVKGQCAKVS SINDKSDWKV VRKALTVIDF TEDEVEDLLS IVASVLHLGN IHFAANEESN AQVTTENQLK YLTRLLSVEG STLREALTHR KIIAKGEELL SPLNLEQAAY ARDALAKAVY SRTFTWLV
Target Information
MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ23903; MMI-beta; Myosin I beta; myosin-I beta; myosin-Ic; nuclear myosin I; Unconventional myosin-Ic
Gene Aliases: MMI-beta; MMIb; MYO1C; myr2; NMI
UniProt ID: (Human) O00159
Entrez Gene ID: (Human) 4641
protein targeting
protein targeting to membrane
positive regulation of cell migration
positive regulation of cell migration by vascular endothelial growth factor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of gene expression, epigenetic
mRNA transport
positive regulation of protein targeting to membrane
positive regulation of vascular endothelial growth factor signaling pathway
regulation of bicellular tight junction assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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