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MYO1C Antibody (PA5-93297) in IHC (P)
Immunohistochemistry analysis of MYO1C in paraffin-embedded mouse kidney. Samples were incubated with MYO1C Polyclonal antibody (Product # PA5-93297) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-93297
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 769-1028 of human MYO1C (NP_2036933)
Conjugate
Form
Liquid
Concentration
0.95 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806708
Product Specific Information
Immunogen sequence: ENAFFLDHVR TSFLLNLRRQ LPQNVLDTSW PTPPPALREA SELLRELCIK NMVWKYCRSI SPEWKQQLQQ KAVASEIFKG KKDNYPQSVP RLFISTRLGT DEISPRVLQA LGSEPIQYAV PVVKYDRKGY KPRSRQLLLT PNAVVIVEDA KVKQRIDYAN LTGISVSSLS DSLFVLHVQR ADNKQKGDVV LQSDHVIETL TKTALSANRV NSININQGSI TFAGGPGRDG TIDFTPGSEL LITKAKNGHL AVVAPRLNSR; Positive Samples: HT-29, SKOV3, Mouse lung, Rat lung; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Nucleus, Nucleus, Peripheral membrane protein, nuclear pore complex, nucleolus, nucleoplasm, ruffle, stereocilium membrane
Target Information
MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ23903; MMI-beta; MMIb; Myosin heavy chain myr 2; Myosin I beta; myosin IC-like; myosin-I beta; myosin-Ibeta; myosin-Ic; nuclear myosin I; nuclear myosin I beta; unconventional myosin Myr2 I heavy chain; Unconventional myosin-Ic
Gene Aliases: C80397; mm1beta; MMI-beta; MMIb; MYO1C; MYO1E; Myr2; NMI
UniProt ID: (Human) O00159, (Rat) Q63355, (Mouse) Q9WTI7
Entrez Gene ID: (Human) 4641, (Rat) 65261, (Mouse) 17913
protein targeting
protein targeting to membrane
positive regulation of cell migration
positive regulation of cell migration by vascular endothelial growth factor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of gene expression, epigenetic
mRNA transport
positive regulation of protein targeting to membrane
positive regulation of vascular endothelial growth factor signaling pathway
regulation of bicellular tight junction assembly
transport
metabolic process
protein transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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