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产品信息
PA5-81932
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2789093
产品详细信息
Immunogen sequence: QNLQLPPEAR IEASLQHEIT RLTNENLDLM EQLEKQDKTV RKLKKQLKVF AKKIGELEVG QMENISPGQI IDEPIRPVNI PRKEKDFQGM LEYKKEDEQK LVKNLILELK PRGVAVNLIP G
靶标信息
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dilute myosin heavy chain, non-muscle; Myosin heavy chain 12; myosin V; myosin VA (heavy chain 12, myoxin); myosin, heavy polypeptide kinase; Myosin-12; myosin-Va; Myoxin; OTTMUSP00000017756; OTTMUSP00000019176; OTTMUSP00000046608; Unconventional myosin-Va
基因别名: GS1; MYH12; MYO5; MYO5A; MYR12
UniProt ID: (Human) Q9Y4I1
Entrez Gene ID: (Human) 4644
transport
exocytosis
post-Golgi vesicle-mediated transport
chemical synaptic transmission
visual perception
vesicle-mediated transport
actin filament-based movement
vesicle transport along actin filament
insulin secretion
melanocyte differentiation
regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
locomotion involved in locomotory behavior
secretory granule localization
melanosome transport
cellular response to insulin stimulus
odontogenesis
myelination
long-chain fatty acid biosynthetic process
synapse organization
endoplasmic reticulum localization
protein localization to plasma membrane
regulation of Golgi organization
