Invitrogen

MYO5B Polyclonal Antibody

MYO5B Antibody in Immunohistochemistry (IHC)

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MYO5B Antibody (PA5-59212) in IHC

Immunohistochemical staining of MYO5B in human colon, kidney, lymph node and testis using MYO5B Polyclonal Antibody (Product # PA5-59212) (A) shows similar protein distribution across tissues to an independent MYO5B Polyclonal Antibody (B).

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MYO5B Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of MYO5B demonstrates antibody specificity. Immunohistochemical analysis of MYO5B using anti-MYO5B Polyclonal Antibody (Product # PA5-59212), shows significant staining of MYO5B in human small intestine and shows minimal or weak staining in human skeletal muscle tissues. The relative expression levels of MYO5B within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-59212

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

1:200-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human MYO5B. Recombinant protein control fragment (Product #RP-98268).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2644373

产品详细信息

Immunogen sequence: VTTSTYTMEV ERLKKELVHY QQSPGEDTSL RLQEEVESLR TELQRAHSER KILEDAHSRE KDELRKRVAD LEQENALLKD EKEQLNNQIL CQSK

Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 74%.

靶标信息

May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。