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Product Details
PA5-59344
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MYO5B. Recombinant protein control fragment (Product #RP-98269).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2644374
Product Specific Information
Immunogen sequence: NLMKKELEEE RSRYQNLVKE YSQLEQRYDN LRDEMTIIKQ TPGHRRNPSN QSSLESDSNY PSISTSEIGD TEDALQQVEE IGLEKAAMDM TVFLK
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 89%.
Target Information
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MYO5B variant protein; myosin-Vb; Unconventional myosin-Vb
Gene Aliases: KIAA1119; MYO5B
UniProt ID: (Human) Q9ULV0
Entrez Gene ID: (Human) 4645
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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