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产品信息
PA5-57390
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644397
产品详细信息
Immunogen sequence: LEELSHLSNR GARLFKMRQR RSDKYTFENF QYQSRAQINH SIAMQNGKVD GSNLEGGSQQ APLTPPNTPD PR
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 85%.
靶标信息
The calcineurin-binding protein Myozenin 2, also designated calsarcin-1, is a member of the calsarcin protein family. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase that is involved in controlling the slow fiber gene expression in skeletal muscle and hypertrophy of cardiac muscle. The calsarcins are sarcomeric proteins that couple calcineurin and muscle activity. In cardiac and skeletal muscle cells, Myozenin 2 binds calcineurin to α-actinin at the Z-line of the sarcomere. During embryogenesis, Myozenin 1 and 2 are expressed in developing muscle. The Myozenin 2 gene maps to chromosome 4q and is expressed specifically in adult cardiac and slow-twitch skeletal muscle, while Myozenin 1 is only detected in fast skeletal muscle.
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生物信息学
蛋白别名: calcineurin-binding protein calsarcin-1; Calsarcin-1; FATZ-related protein 2; muscle-specific protein; MYOZ2; Myozenin-2
基因别名: C4orf5; CMH16; CS-1; MYOZ2
UniProt ID: (Human) Q9NPC6
Entrez Gene ID: (Human) 51778
