Invitrogen

Macro H2A.2 Polyclonal Antibody

Macro H2A.2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Macro H2A.2 Antibody (PA5-30648) in IHC (P)

Immunohistochemistry (Paraffin) analysis of Macro H2A.2 was performed in paraffin-embedded mouse brain tissue using Macro H2A.2 Polyclonal Antibody (Product # PA5-30648) at a dilution of 1:500.

Macro H2A.2 Antibody in Western Blot (WB)

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产品信息

PA5-30648

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

免疫组化（石蜡） (IHC (P))

1:100-1:1,000

免疫细胞化学 (ICC/IF)

1:100-1:1,000

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fragment corresponding to a region within amino acids 147 and 370 of Human Macro H2A.2

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7, with 1% BSA, 20% glycerol

内含物

0.01% thimerosal

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2548122

产品详细信息

Recommended positive controls: mouse brain, human H2AFY2-transfected 293T.

Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (84%), Chicken (95%), Rhesus Monkey (100%), Bovine (100%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

靶标信息

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。