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Melatonin Receptor 1A (MTNR1A) Polyclonal Antibody

Melatonin Receptor 1A (MTNR1A) Antibody in Immunohistochemistry (IHC)

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Melatonin Receptor 1A (MTNR1A) Antibody (AMR-031-200UL) in IHC

Expression of Melatonin receptor type 1A in rat supra-chiasmatic nucleus - Immunohistochemical staining of rat supra-chiasmatic nucleus (SCN) with Anti-Melatonin Receptor 1A (MTNR1A) Antibody (#AMR-031). A. MT1 staining is restricted to the SCN (red). B. DAPI is used as the counterstain (blue). C. Merge of A and B.

Melatonin Receptor 1A (MTNR1A) Antibody in Western Blot (WB)

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产品信息

AMR-031-200UL

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

免疫组化 (IHC)

Assay-dependent

产品规格

种属反应

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

(C)RVKPDNKPKLKPQD, corresponding to amino acid residues 223-236 of mouse MTNR1A, 3rd intracellular loop

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.8 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

靶标信息

This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

仅用于科研。不用于诊断过程。未经明确授权不得转售。