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产品信息
PA5-31137
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 276 of Human Mig-6
偶联物
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548611
产品详细信息
Recommended positive controls: HCT116.
Predicted reactivity: Rhesus Monkey (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ERBB receptor feedback inhibitor 1; MIG-6; Mitogen-inducible gene 6 protein; Mitogen-inducible gene 6 protein homolog; receptor-associated late transducer
基因别名: 1300002F13Rik; AI788755; ERRFI1; GENE-33; MIG-6; MIG6; RALT
UniProt ID: (Human) Q9UJM3, (Mouse) Q99JZ7
Entrez Gene ID: (Human) 54206, (Mouse) 74155
negative regulation of epidermal growth factor-activated receptor activity
stress-activated protein kinase signaling cascade
negative regulation of protein autophosphorylation
negative regulation of interleukin-1 beta production
negative regulation of collagen biosynthetic process
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of tumor necrosis factor biosynthetic process
skin morphogenesis
regulation of keratinocyte differentiation
lung alveolus development
negative regulation of peptidyl-tyrosine phosphorylation
lung vasculature development
lung epithelium development
regulation of type B pancreatic cell proliferation
negative regulation of ERK1 and ERK2 cascade
negative regulation of cardiac muscle hypertrophy in response to stress
response to stress
cellular response to insulin stimulus
cellular response to platelet-derived growth factor stimulus
positive regulation of GTPase activity
cellular response to epidermal growth factor stimulus
cellular hyperosmotic response
cellular response to dexamethasone stimulus
