Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 2
Myb Antibody (PA5-101014) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Myb in mouse liver tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Myb polyclonal antibody (Product # PA5-101014) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-101014
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MYB(Accession P10242), corresponding to amino acid residues S506-F556.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2850490
Product Specific Information
Antibody detects endogenous levels of total c-Myb.
Target Information
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; gag-myb protein; myb proto-oncogene protein; myeloblastosis proto-oncogene product; oncogene AMV; Proto-oncogene c-Myb; RP1-32B1.1; Transcriptional activator Myb; tumor-specific myb protein; v-myb avian myeloblastosis viral oncogene homolog
Gene Aliases: AI550390; c-myb; c-myb_CDS; Cmyb; efg; M16449; MYB
UniProt ID: (Human) P10242, (Mouse) P06876
Entrez Gene ID: (Human) 4602, (Mouse) 17863
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, RNA polymerase II transcription factor recruiting
protein binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
WD40-repeat domain binding
negative regulation of transcription from RNA polymerase II promoter
mitotic cell cycle
chromatin remodeling
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
positive regulation of T-helper cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of histone H3-K4 methylation
positive regulation of histone H3-K9 methylation
G1/S transition of mitotic cell cycle
in utero embryonic development
transcription, DNA-templated
calcium ion transport
regulation of gene expression
B cell differentiation
thymus development
embryonic digestive tract development
homeostasis of number of cells
cellular response to interleukin-6
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support