Invitrogen

Myb Polyclonal Antibody

Myb Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Myb Antibody (PA5-101014) in IHC (P)

Immunohistochemistry analysis of paraffin-embedded Myb in mouse liver tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Myb polyclonal antibody (Product # PA5-101014) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.

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产品信息

PA5-101014

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

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免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

Assay-dependent

产品规格

种属反应

Human, Mouse

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human MYB(Accession P10242), corresponding to amino acid residues S506-F556.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2850490

产品详细信息

Antibody detects endogenous levels of total c-Myb.

靶标信息

Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

MiR-150-5p Overexpression in Triple-Negative Breast Cancer Contributes to the In Vitro Aggressiveness of This Breast Cancer Subtype.

Cancers

Sugita BM,Rodriguez Y,Fonseca AS,Nunes Souza E,Kallakury B,Cavalli IJ,Ribeiro EMSF,Aneja R,Cavalli LR

PA5-101014 was used in Western Blotting to investigate the expression levels and role of miR-150-5p in the aggressive breast cancer subtype triple-negative breast cancer (TNBC).

Tue Apr 26 00:00:00 UTC 2022

生物信息学

蛋白别名: c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; gag-myb protein; myb proto-oncogene protein; myeloblastosis proto-oncogene product; oncogene AMV; Proto-oncogene c-Myb; RP1-32B1.1; Transcriptional activator Myb; tumor-specific myb protein; v-myb avian myeloblastosis viral oncogene homolog

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基因别名: AI550390; c-myb; c-myb_CDS; Cmyb; efg; M16449; MYB

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UniProt ID: (Human) P10242, (Mouse) P06876

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Entrez Gene ID: (Human) 4602, (Mouse) 17863

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功能

RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, RNA polymerase II transcription factor recruiting protein binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding WD40-repeat domain binding

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