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Invitrogen
Myosin Heavy Chain Recombinant Rabbit Monoclonal Antibody (6V0G1)
FIGURE: 1 / 4
Myosin Heavy Chain Antibody (MA5-35613) in IHC (P)
Immunohistochemistry analysis of Myosin Heavy Chain in paraffin-embedded mouse heart. Samples were incubated with Myosin Heavy Chain Monoclonal antibody (Product # MA5-35613) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
MA5-35613
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
6V0G1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1400 of human Myosin heavy chain (P12883)
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2849513
Product Specific Information
Immunogen sequence: VAELGEQIDN LQRVKQKLEK EKSEFKLELD DVTSNMEQII KAKANLEKMC RTLEDQMNEH RSKAEETQRS VNDLTSQRAK LQTENGELSR QLDEKEALIS QLTRGKLTYT QQLEDLKRQL EEEVKAKNAL AHALQSARHD CDLLREQYEE ETEAKAELQR VLSKANSEVA QWRTKYETDA IQRTEELEEA KKKLAQRLQE A
Target Information
The function of Mhc is muscle contraction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha cardiac MHC; alpha myosin; cardiac myosin heavy chain alpha isoform; cardiomyopathy, hypertrophic 1; epididymis luminal protein 71; MyHC-2x; MyHC-alpha; MyHC-IIx/d; Myosin heavy chain 1; Myosin heavy chain 2x; Myosin heavy chain 6; Myosin heavy chain IIx/d; myosin heavy chain polypeptide 6 cardiac muscle adult; Myosin heavy chain, cardiac muscle alpha isoform; Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha); myosin heavy chain, cardiac muscle, adult; myosin heavy chain, polypeptide 6, cardiac muscle, alpha; Myosin heavy chain, skeletal muscle, adult 1; myosin, heavy chain 1, skeletal muscle, adult; myosin, heavy polypeptide 1, skeletal muscle, adult; myosin, heavy polypeptide 6, cardiac muscle, alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); Myosin-1; Myosin-6; type 2X myosin heavy chain
Gene Aliases: A530084A17Rik; A830009F23Rik; AA517445; alpha-MHC; ASD3; CMD1EE; CMH14; HEL71; IId; IId/x; MdMs; MHC-2X/D; MHC2X/D; MYH1; MYH6; MYHa; MYHC; MyHC-2x; MyHC-2X/D; Myhc-a; MyHC-IId/x; MYHC-IIX; MyHC-IIx/d; MYHCA; Myhs-f; Myhs-f2; MYHSA1; Myhsf2; SSS3
UniProt ID: (Human) P12882, (Human) P13533, (Mouse) Q5SX40, (Mouse) Q02566
Entrez Gene ID: (Human) 4619, (Human) 4624, (Mouse) 17879, (Rat) 287408, (Mouse) 17888, (Rat) 29556
motor activity
actin binding
protein binding
calmodulin binding
ATP binding
microfilament motor activity
ATPase activity
myosin phosphatase activity
protein kinase binding
actin-dependent ATPase activity
nucleotide binding
calcium-dependent ATPase activity
identical protein binding
protein homodimerization activity
protein heterodimerization activity
in utero embryonic development
regulation of the force of heart contraction
regulation of heart rate
muscle contraction
striated muscle contraction
adult heart development
visceral muscle development
regulation of heart contraction
metabolic process
regulation of blood pressure
actin filament-based movement
muscle filament sliding
myofibril assembly
BMP signaling pathway
regulation of ATPase activity
sarcomere organization
ATP metabolic process
cardiac muscle fiber development
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
canonical Wnt signaling pathway
regulation of heart growth
response to heat
protein dephosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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