Invitrogen

Myostatin Polyclonal Antibody

Myostatin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Myostatin Antibody (PA5-11936) in IHC (P)

Immunohistochemistry analysis of Myostatin in formalin-fixed and paraffin-embedded human skeletal muscle tissue. Samples were incubated with Myostatin polyclonal antibody (Product # PA5-11936) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

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产品信息

PA5-11936

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:2,000

查看4篇已发表文章 4篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50

产品规格

种属反应

Human, Mouse

已发表种属

Mouse, Sheep

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human Myostatin (GDF8)

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Antigen affinity chromatography, Protein A

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2235727

产品详细信息

This antibody is predicted to react with bovine, porcine and non-human primate based on sequence homology.

靶标信息

The protein encoded by this gene is a member of the bone morphogenetic protein family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Effects of American wild ginseng and Korean cultivated wild ginseng pharmacopuncture extracts on the regulation of C2C12 myoblasts differentiation through AMPK and PI3K/Akt/mTOR signaling pathway.

Molecular medicine reports

Hwang JH,Kang SY,Jung HW

PA5-11936 was used in Western Blot to investigate ginseng pharmacopuncture to treat impaired myogenesis.

Wed Jun 01 00:00:00 UTC 2022

Monotropein Improves Dexamethasone-Induced Muscle Atrophy via the AKT/mTOR/FOXO3a Signaling Pathways.

Nutrients

Wang P,Kang SY,Kim SJ,Park YK,Jung HW

PA5-11936 was used in Western Blotting to investigate the effects of monotropein (MON) on improving dexamethasone (DEX)-induced muscle atrophy in mice and C2C12 mouse skeletal muscle cells.

Fri Apr 29 00:00:00 UTC 2022

Monotropein Improves Dexamethasone-Induced Muscle Atrophy via the AKT/mTOR/FOXO3a Signaling Pathways.

Nutrients

Wang P,Kang SY,Kim SJ,Park YK,Jung HW

PA5-11936 was used in Western Blotting to investigate the effects of monotropein (MON) on improving dexamethasone (DEX)-induced muscle atrophy in mice and C2C12 mouse skeletal muscle cells.