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Myotilin Antibody (PA5-58081) in IHC
Immunohistochemical staining of Myotilin in human cerebral cortex, lymph node, skeletal muscle and testis using Myotilin Polyclonal Antibody (Product # PA5-58081) (A) shows similar protein distribution across tissues to an independent Myotilin Polyclonal Antibody (B).
产品信息
PA5-58081
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human Myotilin. Recombinant protein control fragment (Product #RP-96838).
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644391
产品详细信息
Immunogen sequence: MSSSAFPASP QQHAGSNPGQ RVTTTYNQSP ASFLSSILPS QPDYNSSKIP SAMDSNYQQS SAGQPINAKP SQTANAKPIP RTPDHEIQG
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 79%.
靶标信息
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 57 kDa cytoskeletal protein; Myofibrillar titin-like Ig domains protein; Myotilin; Titin immunoglobulin domain protein; titin immunoglobulin domain protein (myotilin)
基因别名: LGMD1; LGMD1A; MFM3; MYOT; TTID; TTOD
UniProt ID: (Human) Q9UBF9
Entrez Gene ID: (Human) 9499
