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产品信息
MA5-24520
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1F3
抗原
MTPN (AAH28093, 1 a.a. ~ 118 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2633492
产品详细信息
Peptide Sequence: MCDKEFMWAL KNGGLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPD GLTAFEATDN QAIKALLQ
靶标信息
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6. 4 kDa tumor antigen that is associated with myeloproliferative disease.
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生物信息学
蛋白别名: granule cell differentiation protein; Myotrophin; Protein V-1
基因别名: GCDP; MTPN; V-1
UniProt ID: (Human) P58546
Entrez Gene ID: (Human) 136319
regulation of translation
catecholamine metabolic process
positive regulation of macromolecule biosynthetic process
positive regulation of cardiac muscle hypertrophy
cell growth
regulation of striated muscle tissue development
cerebellar granule cell differentiation
neuron differentiation
positive regulation of cell growth
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
striated muscle cell differentiation
positive regulation of protein metabolic process
cellular response to mechanical stimulus
regulation of barbed-end actin filament capping
