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产品信息
PA5-59419
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644411
产品详细信息
Immunogen sequence: QEEARNKAGT PVSELTKQMD TVLSSSPDVL FDPINGLTPD EEALSNERIC QKRRFSDSEE RHTKKQFSLE NVQEGEILHD AKTLAGNVIA DLSDSSADSE NLSPDI
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 73%.
靶标信息
Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: N4BP1; NEDD4-binding protein 1
基因别名: KIAA0615; N4BP1
UniProt ID: (Human) O75113
Entrez Gene ID: (Human) 9683
