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NASP Antibody (PA5-93299) in IHC (P)
Immunohistochemistry analysis of NASP in paraffin-embedded human brain astrocytoma. Samples were incubated with NASP Polyclonal antibody (Product # PA5-93299) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-93299
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 180-449 of human NASP (NP_6895112)
偶联物
形式
Liquid
浓度
0.22 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806709
产品详细信息
Immunogen sequence: WDMLDLAKII FKRQETKEAQ LYAAQAHLKL GEVSVESENY VQAVEEFQSC LNLQEQYLEA HDRLLAETHY QLGLAYGYNS QYDEAVAQFS KSIEVIENRM AVLNEQVKEA EGSSAEYKKE IEELKELLPE IREKIEDAKE SQRSGNVAEL ALKATLVESS TSGFTPGGGG SSVSMIASRK PTDGASSSNC VTDISHLVRK KRKPEEESPR KDDAKKAKQE PEVNGGSGDA VPSGNEVSEN MEEEAENQAE SRAAVEGTVE AGATVESTAC; Positive Samples: SW620, HL-60, 293T; Cellular Location: Cytoplasm, Nucleus
靶标信息
NASP encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp547F162; FLJ31599; FLJ35510; histone H1-binding protein; MGC19722; MGC20372; MGC2297; NASP; NASP histone chaperone; nasp {ECO:0000312|EMBL:AAH81913.1}; Nuclear autoantigenic sperm protein; nuclear autoantigenic sperm protein (histone-binding); somatic histone binding protein NASP
基因别名: 5033430J04Rik; AI131596; AI317140; D4Ertd767e; Epcs32; FLB7527; HMDRA1; NASP; Nasp-T; PRO1999
UniProt ID: (Human) P49321, (Rat) Q66HD3, (Mouse) Q99MD9
Entrez Gene ID: (Human) 4678, (Rat) 298441, (Mouse) 50927
