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Immunogen sequence: DLTKTNMQTM YEQSEWGWKD REKREEMTDD RAWYLIAWEN SSVPVAFSHF RFDVECGDEV LYCYEVQLES KV
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 97%.
N-terminal acetylation is one of the most common protein modifications in eukaryotes, occurring on approximately 57% and 84% on yeast and human proteins respectively. There are several N-terminal acetylating enzyme complexes (NatA - NatE). Unlike the other complexes, NatD is composed of a single protein, NAT11, and has recently been described to acetylate the Serine N-termini of histones H2A and H4 in yeast. The role these modifications play is unknown; yeast that do not express NAT11 grow at normal rates and have no observable phenotypes. The role of the human homolog is likewise unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog; N-acetyltransferase 11; N-acetyltransferase 11 (GCN5-related, putative); N-alpha acetyl transferase 40; N-alpha-acetyltransferase 40; N-alpha-acetyltransferase 40, NatD catalytic subunit; N-alpha-acetyltransferase D; NatD; natD catalytic subunit; Protein acetyltransferase 1
Gene Aliases: NAA40; NAT11; PATT1
UniProt ID: (Human) Q86UY6
Entrez Gene ID: (Human) 79829
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