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NCBP1 Antibody (PA5-115624) in ICC/IF
Immunocytochemistry analysis of NCBP1 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115624). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
产品信息
PA5-115624
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NCBP1(Accession Q09161), corresponding to amino acid residues M1-I35.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2900259
产品详细信息
Antibody detects endogenous levels of total NCBP1.
靶标信息
May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 80 kDa nuclear cap-binding protein; CBP80; MGC2087; NCBP 80 kDa subunit; nuclear cap binding protein subunit 1, 80kD; nuclear cap binding protein subunit 1, 80kDa; Nuclear cap-binding protein subunit 1; RP11-546O6.1
基因别名: AU014645; AW538051; CBP80; NCBP; NCBP1; Sto1
UniProt ID: (Human) Q09161, (Rat) Q56A27, (Mouse) Q3UYV9
Entrez Gene ID: (Human) 4686, (Rat) 298075, (Mouse) 433702
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
mRNA splicing, via spliceosome
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
termination of RNA polymerase II transcription
7-methylguanosine mRNA capping
RNA export from nucleus
mRNA export from nucleus
regulation of translational initiation
histone mRNA metabolic process
RNA splicing
fibroblast growth factor receptor signaling pathway
gene expression
positive regulation of cell growth
gene silencing by RNA
mRNA 3'-end processing
positive regulation of mRNA 3'-end processing
snRNA transcription from RNA polymerase II promoter
mRNA cis splicing, via spliceosome
nuclear export
pre-mRNA cleavage required for polyadenylation
regulation of mRNA polyadenylation
mRNA cleavage
biological_process
mRNA processing
regulation of translation
transport
RNA metabolic process
mRNA transport
