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产品信息
PA5-30451
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 156 of Human NCBP2
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2547925
产品详细信息
Recommended positive controls: mouse brain.
Predicted reactivity: Mouse (97%), Rat (97%), Zebrafish (83%), Xenopus laevis (86%), Chicken (89%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 20 kDa nuclear cap-binding protein; CBP20; Cell proliferation-inducing gene 55 protein; NCBP 20 kDa subunit; NCBP interacting protein 1; NCBP-interacting protein 1; NIP1; nuclear cap binding protein subunit 2, 20kD; nuclear cap binding protein subunit 2, 20kDa; Nuclear cap-binding protein subunit 2
基因别名: 20kDa; 5930413E18Rik; AA536802; AI843301; C79367; CBC2; CBP20; NCBP2; NIP1; PIG55
UniProt ID: (Human) P52298, (Mouse) Q9CQ49
Entrez Gene ID: (Human) 22916, (Mouse) 68092
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
mRNA splicing, via spliceosome
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
termination of RNA polymerase II transcription
7-methylguanosine mRNA capping
RNA export from nucleus
mRNA export from nucleus
snRNA export from nucleus
regulation of translational initiation
histone mRNA metabolic process
RNA splicing
fibroblast growth factor receptor signaling pathway
gene expression
gene silencing by RNA
mRNA 3'-end processing
positive regulation of mRNA 3'-end processing
snRNA transcription from RNA polymerase II promoter
mRNA cis splicing, via spliceosome
positive regulation of RNA export from nucleus
nuclear export
pre-mRNA cleavage required for polyadenylation
regulation of mRNA polyadenylation
mRNA processing
regulation of translation
transport
mRNA transport
