Invitrogen

NCEH1 Polyclonal Antibody

NCEH1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 5

NCEH1 Antibody (PA5-50285) in IHC (P)

Immunohistochemical analysis of NCEH1 in paraffin embedded Human lung cancer tissue using NCEH1 Polyclonal Antibody (Product # PA5-50285) at a 1:80 dilution.

Product Image Gallery

产品信息

PA5-50285

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:5,000

查看2篇已发表文章 2篇已发表文章

免疫组化（石蜡） (IHC (P))

1:100-1:300

产品规格

种属反应

Human, Mouse

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Fusion protein corresponding to residues near the C terminal of human Neutral cholesterol ester hydrolase 1

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

2.6 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 40% glycerol

内含物

0.05% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2635738

产品详细信息

The antibody detects endogenous levels of total NCEH1 protein.

靶标信息

Neutral cholesterol ester hydrolase 1 (NCEH) also known as arylacetamide deacetylase-like 1 (AADACL1) or KIAA1363 is an enzyme that in humans is encoded by the NCEH1 gene. NCEH is an enzyme located in the endoplasmic reticulum. NCEH hydrolyzes 2-acetyl monoalkylglycerol ether, as part of an enzymatic pathway regulating the levels of platelet activating factor and lysophospholipids that may be involved in cancer development.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells.

Journal of lipid research

Wagner C,Hois V,Eggeling A,Pusch LM,Pajed L,Starlinger P,Claudel T,Trauner M,Zimmermann R,Taschler U,Lass A

PA5-50285 was used in Western Blot to identify KIAA1363 (also annotated as arylacetamide deacetylase 1 or neutral cholesterol ester hydrolase 1) as a novel RE hydrolase.

Tue Mar 01 00:00:00 UTC 2022

KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells.

Journal of lipid research

Wagner C,Hois V,Eggeling A,Pusch LM,Pajed L,Starlinger P,Claudel T,Trauner M,Zimmermann R,Taschler U,Lass A

PA5-50285 was used in Western Blot to identify KIAA1363 (also annotated as arylacetamide deacetylase 1 or neutral cholesterol ester hydrolase 1) as a novel RE hydrolase.

Tue Mar 01 00:00:00 UTC 2022

KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells.

Journal of lipid research

Wagner C,Hois V,Eggeling A,Pusch LM,Pajed L,Starlinger P,Claudel T,Trauner M,Zimmermann R,Taschler U,Lass A

PA5-50285 was used in Western Blot to identify KIAA1363 (also annotated as arylacetamide deacetylase 1 or neutral cholesterol ester hydrolase 1) as a novel RE hydrolase.

Tue Mar 01 00:00:00 UTC 2022

Retinoic acid receptor-related orphan receptor α reduces lipid droplets by upregulating neutral cholesterol ester hydrolase 1 in macrophages.

BMC molecular and cell biology

Matsuoka H,Tokunaga R,Katayama M,Hosoda Y,Miya K,Sumi K,Ohishi A,Kamishikiryo J,Shima A,Michihara A

PA5-50285 was used in Western Blotting to study the mechanisms regulating NCHE1 expression within macrophages, with a focus of RORa inhibition using RORa-deficient mice.

Wed Apr 22 00:00:00 UTC 2020

Retinoic acid receptor-related orphan receptor α reduces lipid droplets by upregulating neutral cholesterol ester hydrolase 1 in macrophages.

BMC molecular and cell biology

Matsuoka H,Tokunaga R,Katayama M,Hosoda Y,Miya K,Sumi K,Ohishi A,Kamishikiryo J,Shima A,Michihara A

PA5-50285 was used in Western Blotting to study the mechanisms regulating NCHE1 expression within macrophages, with a focus of RORa inhibition using RORa-deficient mice.

Wed Apr 22 00:00:00 UTC 2020

生物信息学

蛋白别名: 2-acetyl MAGE hydrolase; Acetylalkylglycerol acetylhydrolase; Arylacetamide deacetylase-like 1; Chlorpyrifos oxon-binding protein; CPO-BP; NCEH; Neutral cholesterol ester hydrolase 1

查看更多收起

基因别名: AADACL1; B230106I24Rik; CPO-BP; KIAA1363; NCEH; NCEH1

查看更多收起

UniProt ID: (Human) Q6PIU2, (Mouse) Q8BLF1

查看更多收起

Entrez Gene ID: (Human) 57552, (Mouse) 320024

查看更多收起

功能