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产品信息
PA5-31121
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 203 of Human NDE1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548595
产品详细信息
Recommended positive controls: IMR32.
Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (80%), Xenopus laevis (82%), Dog (99%), Chicken (90%), Rhesus Monkey (100%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
NDE1 is s a member of the nuclear distribution E (NudE) family of proteins. It is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. NDE1 protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations to the gene lead to Lissencephaly 4 (LIS4) and Microhydranencephaly (MHAC).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: LIS1-interacting protein NUDE1, rat homolog; Nuclear distribution protein nudE homolog 1; NudE; nudE nuclear distribution E homolog 1; nudE nuclear distribution gene E homolog 1
基因别名: HOM-TES-87; LIS4; MHAC; NDE; NDE1; NUDE; NUDE1
UniProt ID: (Human) Q9NXR1
Entrez Gene ID: (Human) 54820
G2/M transition of mitotic cell cycle
establishment of mitotic spindle orientation
neuron migration
microtubule nucleation
chromosome segregation
sister chromatid cohesion
mitotic centrosome separation
neuroblast proliferation
cell migration
cerebral cortex development
vesicle transport along microtubule
centrosome duplication
cell division
establishment of chromosome localization
centrosome localization
regulation of microtubule motor activity
