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NDE1 Antibody (711424) in WB
Western blot analysis was performed on Tissue extracts (30 µg lysate) of Mouse brain (Lane 1), Rat brain (Lane 2) and whole cell extracts of Neuro2a (Lane 3), IMR32 (Lane 4), T98G (Lane 5), NIH/3T3 (Lane 6), HeLa (Lane 7) and HepG2 (Lane 8). The blots were probed with Anti-Nde1 Recombinant Rabbit Superclonal™ Antibody (Product # 711424, 1 µg/mL). A 40 kDa band corresponding to Nde1 was observed across the cell lines and tissues tested. The blots were detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Second... View More
产品信息
711424
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Superclonal
类型
Antibody
抗原
Protein corresponding to human NDE1 (aa1-aa346)
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2692258
产品详细信息
This antibody is predicted to react with Monkey, Cat, and Horse.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Note: Formerly called “Recombinant polyclonal antibody”, this product is now rebranded as “Recombinant Superclonal™ antibody”. The physical product and the performance remain unchanged.
靶标信息
NDE1 is s a member of the nuclear distribution E (NudE) family of proteins. It is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. NDE1 protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations to the gene lead to Lissencephaly 4 (LIS4) and Microhydranencephaly (MHAC).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: LIS1-interacting protein NUDE1; LIS1-interacting protein NUDE1, rat homolog; nuclear distribution gene E homolog 1; Nuclear distribution protein nudE homolog 1; NudE; nudE nuclear distribution E homolog 1; nudE nuclear distribution gene E homolog 1; rNudE
基因别名: 2810027M15Rik; AU042936; AW822251; HOM-TES-87; LIS4; MHAC; mNudE; NDE; NDE1; NUDE; NUDE1
UniProt ID: (Human) Q9NXR1, (Rat) Q9ES39, (Mouse) Q9CZA6
Entrez Gene ID: (Human) 54820, (Rat) 83836, (Mouse) 67203
establishment of mitotic spindle orientation
neuron migration
microtubule nucleation
chromosome segregation
mitotic centrosome separation
neuroblast proliferation
cell migration
cerebral cortex development
forebrain development
microtubule organizing center organization
vesicle transport along microtubule
centrosome duplication
cell division
establishment of chromosome localization
centrosome localization
cell cycle
mitotic nuclear division
multicellular organism development
nervous system development
cell differentiation
G2/M transition of mitotic cell cycle
sister chromatid cohesion
regulation of microtubule motor activity
