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产品信息
PA5-102534
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human NDP(Accession Q00604), corresponding to amino acid residues G67-T117.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2851936
产品详细信息
Antibody detects endogenous levels of total NDP.
靶标信息
ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Norrie disease (pseudoglioma); Norrie disease homolog; Norrie disease protein; Norrie disease protein homolog; Norrin; X-linked exudative vitreoretinopathy 2 protein
基因别名: EVR2; FEVR; ND; NDP; Ndph; RGD1563968
UniProt ID: (Human) Q00604, (Mouse) P48744
Entrez Gene ID: (Human) 4693, (Mouse) 17986, (Rat) 363443
placenta development
vacuole organization
signal transduction
cell-cell signaling
nervous system development
visual perception
sensory perception of sound
cell proliferation
Wnt signaling pathway
extracellular matrix-cell signaling
positive regulation of transcription, DNA-templated
positive regulation of sequence-specific DNA binding transcription factor activity
canonical Wnt signaling pathway
retina vasculature morphogenesis in camera-type eye
decidualization
