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产品信息
PA5-120431
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 140-220 of human NDRG4 (NP_001229765.1).
偶联物
形式
Liquid
浓度
2.35 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2914003
产品详细信息
Positive test controls include: Mouse brain, Rat brain. The target is usually found in the following locations: Cytoplasm, cytosol.
Immunogen sequence: DPNGKGWIDW AATKLSGLTS TLPDTVLSHL FSQEELVNNT ELVQSYRQQI GNVVNQANLQ LFWNMYNSRR DLDINRPGTV P
靶标信息
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may be involved in the regulation of mitogenic signaling in vascular smooth muscles cells. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Brain development-related molecule 1; development-related protein; DKFZp686I1615; FLJ30586; FLJ42011; MGC19632; N-myc downstream regulated 1, related sequence; N-myc downstream regulated 4; N-myc downstream regulated gene 4; N-myc downstream-regulated gene 4 protein; Protein Ndr4; Protein NDRG4; SMAP-8; smooth muscle-associated protein 8; Vascular smooth muscle cell-associated protein 8
基因别名: BDM1; D8Bwg1337e; KIAA1180; Ndr1-rs; Ndr4; NDRG4; R74996; SMAP-8; SMAP8
UniProt ID: (Human) Q9ULP0, (Mouse) Q8BTG7
Entrez Gene ID: (Human) 65009, (Mouse) 234593, (Rat) 64457
heart looping
response to stress
brain development
visual learning
negative regulation of platelet-derived growth factor receptor signaling pathway
positive regulation of neuron projection development
negative regulation of smooth muscle cell migration
cell growth
cell differentiation
embryonic heart tube development
vesicle docking
negative regulation of smooth muscle cell proliferation
cardiac muscle cell proliferation
cell migration involved in heart development
positive regulation of ERK1 and ERK2 cascade
regulation of endocytic recycling
signal transduction
