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Immunogen sequence: YLFLLMHPSI ISNLPSPKTF EEVQFFNGNN YHKGIDWYMD FFPTPSNTTS
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity. [UniProt]
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Protein Aliases: Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4; Glucosaminyl N-deacetylase/N-sulfotransferase 4; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4; N-deacetylase/N-sulfotransferase 4; N-heparan sulfate sulfotransferase 4; N-HSST 4; NDST-4
Gene Aliases: HSST4; N-HSST; N-HSST 4; NDST-4; NDST4; NHSST4
UniProt ID: (Human) Q9H3R1
Entrez Gene ID: (Human) 64579
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