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产品信息
PA5-22364
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 200 and 430 of NDUFS2 (Uniprot ID#O75306)
偶联物
形式
Liquid
浓度
0.43 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152516
产品详细信息
Recommended positive controls: 293T, A431, Jurkat, Raji, mouse brain, rat brain.
Predicted reactivity: Mouse (95%), Rat (94%), Zebrafish (84%), Xenopus laevis (90%), Rhesus Monkey (98%), Chimpanzee (100%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase. Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CI-49kD; comp; complex 1, mitochondrial respiratory chain, 49-KD subunit; complex I 49kDa subunit; Complex I-49kD; NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial; NADH-coenzyme Q reductase; NADH-ubiquinone oxidoreductase 49 kDa subunit; NADH-ubiquinone oxidoreductase NDUFS2 subunit; ndufs2 {ECO:0000312|EMBL:AAH82067.1}
基因别名: AL033311; CI-49; NDUFS2
UniProt ID: (Human) O75306, (Mouse) Q91WD5, (Rat) Q641Y2
Entrez Gene ID: (Human) 4720, (Mouse) 226646, (Rat) 289218
NADH dehydrogenase activity
protein binding
NADH dehydrogenase (ubiquinone) activity
electron carrier activity
ubiquitin protein ligase binding
metal ion binding
quinone binding
NAD binding
4 iron, 4 sulfur cluster binding
oxidoreductase activity
oxidoreductase activity, acting on NAD(P)H
iron-sulfur cluster binding
molecular_function
oxidoreductase
