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产品信息
MA5-38178
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
ARC1784
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human NDUFS4 (O43181)
偶联物
形式
Liquid
浓度
1.37 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2898095
产品详细信息
Positive Samples: Mouse liver, Mouse heart, Rat brain, Rat kidney, Rat heart, HepG2
Immunogen sequence: MAAVSMSVVL RQTLWRRRAV AVAALSVSRV PTRSLRTSTW RLAQDQTQDT QLITVDEKLD ITTLTGVPEE HIKTRKVRIF VPARNNMQSG VNNTKKWKME
靶标信息
This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), or NADH:ubiquinone oxidoreductase, the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. In well-coupled mitochondria, the electron flux leads to ATP generation via the building of a proton gradient across the inner membrane. Complex I is composed of at least 41 subunits, of which 7 are encoded by the mitochondrial genome and the remainder by nuclear genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CI-18 kDa; CI-AQDQ; complex I 18kDa subunit; Complex I-18 kDa; Complex I-AQDQ; mitochondrial respiratory chain complex I (18-KD subunit); NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial; NADH-ubiquinone oxidoreductase 18 kDa subunit
基因别名: 6720411N02Rik; AQDQ; C1-18k; CI-18; CI-18 kDa; CI-AQDQ; NDUFS4
UniProt ID: (Human) O43181, (Mouse) Q9CXZ1, (Rat) Q5XIF3
Entrez Gene ID: (Human) 4724, (Mouse) 17993, (Rat) 499529
regulation of protein phosphorylation
mitochondrial electron transport, NADH to ubiquinone
brain development
cAMP-mediated signaling
mitochondrial respiratory chain complex I assembly
cellular respiration
positive regulation of fibroblast proliferation
response to cAMP
reactive oxygen species metabolic process
transport
electron transport chain
oxidation-reduction process
