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产品信息
PA5-64161
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644576
产品详细信息
Immunogen sequence: TGEKVTHTGQ VYDDKDYRRI RFVGRQK
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 85%.
靶标信息
This gene encodes a subunit of the NADH:ubiquinone oxidoreductase, which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.
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生物信息学
蛋白别名: CI-13kD-A; complex I 13kDa subunit A; complex I, mitochondrial respiratory chain, 13-kD subunit; Complex I-13kD-A; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase); NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; NADH-ubiquinone oxidoreductase 13 kDa-A subunit; NADH:ubiquinone oxidoreductase NDUFS6 subunit
基因别名: CI-13kA; CI-13kD-A; CI13KDA; NDUFS6
UniProt ID: (Human) O75380
Entrez Gene ID: (Human) 4726
mitochondrial electron transport, NADH to ubiquinone
fatty acid metabolic process
muscle contraction
multicellular organism aging
mitochondrial respiratory chain complex I assembly
multicellular organism growth
reproductive system development
mitochondrion morphogenesis
cardiovascular system development
