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Immunogen sequence: NLKAQEDEKG KQNLSDTFEI NVHEDAKEHE KEKSVSSDRK KWEAGGQLVI PLDELTLDTS FSTTERHTVG EVIKLGPNGS PRRAWGKSPT DSVLKILGEA ELQLQTELLE NTTIRSEISP EGEKYKPLIT GEKKVQCISH EINPSA
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 71%.
NEK1 is a serine/threonine protein kinase, related to the NIMA cell cycle regulator, and is highly expressed in meiotic germ cells. The kinase may function early in the DNA damage response pathway. NEK1 may also participate in polycystic kidney disease and neural cell development. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp686D06121; DKFZp686K12169; MGC138800; Never in mitosis A-related kinase 1; NIMA (never in mitosis gene a)-related kinase 1; NIMA-related kinase 1; NimA-related protein kinase 1; NY REN55; protein-serine/threonine kinase; Renal carcinoma antigen NY-REN-55; Serine/threonine-protein kinase Nek1
基因别名: KIAA1901; NEK1; NY-REN-55; SRPS2; SRPS2A; SRTD6
UniProt ID: (Human) Q96PY6
Entrez Gene ID: (Human) 4750