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产品信息
MA5-24947
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI5B9
抗原
Full length human recombinant protein of NEK6 produced in HEK293T cell
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723396
靶标信息
NEK6 kinase is a member of the NEK family. NEK6 is a serine/threonine kinase that controls the initiation of mitosis and is required for the metaphase-anaphase transition. The Aspergillus nidulans 'never in mitosis A' (NIMA) gene encodes a serine/threonine kinase that controls initiation of mitosis. NIMA-related kinases (NEKs) are a group of protein kinases that are homologous to NIMA. Evidence suggests that NEKs perform functions similar to those of NIMA. NEK6 encodes a NEK type protein kinase, which contains a C-terminal NIMA-like catalytic domain.
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生物信息学
蛋白别名: Never in mitosis A-related kinase 6; NIMA (never in mitosis gene a)-related kinase 6; NIMA-related kinase 6; NimA-related protein kinase 6; Protein kinase SID6-1512; putative serine-threonine protein kinase; RP11-101K10.6; Serine/threonine-protein kinase Nek6; SID
基因别名: NEK6; SID6-1512
UniProt ID: (Human) Q9HC98
Entrez Gene ID: (Human) 10783
cytokinesis
protein phosphorylation
apoptotic process
chromosome segregation
mitotic nuclear division
mitotic nuclear envelope disassembly
signal transduction
regulation of mitotic cell cycle
peptidyl-serine phosphorylation
regulation of mitotic metaphase/anaphase transition
G2 DNA damage checkpoint
positive regulation of I-kappaB kinase/NF-kappaB signaling
protein autophosphorylation
spindle assembly
regulation of cellular senescence
