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产品信息
PA5-20577
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 15 amino acid peptide from near the carboxy terminus of human NENF.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11153616
产品详细信息
Despite its predicted molecular weight of ~20kDa, NENF is observed at 37kDa in SDS-PAGE. A suggested positive control is human small intestine tissue lysate.
PA5-20577 can be used with blocking peptide PEP-0697.
靶标信息
NENF is a secreted protein that is expressed in neurons but not glial cells of the brain. This protein has neurotrophic activity in primary cultured mouse neurons but not mitogenic activity in primary cultured mouse astrocytes. NENF activated mitogen-activated protein (MAP) and phosphotidylinositol-3 kinase pathways and could be inhibited by pertussis toxin but not receptor tyrosine kinases, suggesting that NENF acts through a Gi/Go-protein-coupled receptor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell growth-inhibiting protein 47; Cell immortalization-related protein 2; nenf {ECO:0000250|UniProtKB:Q9CQ45}; Neudesin; neuron derived neurotrophic factor; Neuron-derived neurotrophic factor; Protein GIG47; SCIRP10-related protein; Secreted protein of unknown function; Spinal cord injury related protein 10; Spinal cord injury-related protein 10; SPUF protein
基因别名: 1110060M21Rik; CIR2; NENF; SCIRP10; SPUF
UniProt ID: (Human) Q9UMX5, (Rat) Q6IUR5, (Mouse) Q9CQ45
Entrez Gene ID: (Human) 29937, (Rat) 289380, (Mouse) 66208
