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产品信息
PA5-51659
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2644640
产品详细信息
Immunogen sequence: SRNRVIQLST SELGEMELTW QEIMSITELQ GLNAPSEPSF EPQAPAPYLG PPPPTTYCPC SIHPDSGFPL PPPPYELPAS TSHVPDPPYS YGNMAIPVSK PLSLSGLLSE PLQDPLALLD IGLPAGPPKP QEDPES
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 85%.
靶标信息
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Leucine zipper protein NF-E2; nuclear factor (erythroid-derived 2), 45kD; nuclear factor (erythroid-derived 2), 45kDa; Nuclear factor, erythroid-derived 2 45 kDa subunit; p45 NF-E2; Transcription factor NF-E2 45 kDa subunit
基因别名: NF-E2; NFE2; p45
UniProt ID: (Human) Q16621
Entrez Gene ID: (Human) 4778
